Fast drying, film forming iodine release solution

A - Human Necessities – 61 – K

Patent

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Details

A61K 33/18 (2006.01) A01N 59/12 (2006.01) A61K 9/08 (2006.01) A61K 9/70 (2006.01) A61K 47/48 (2006.01) A61L 26/00 (2006.01)

Patent

CA 2231647

This invention relates to a fast drying iodine complex solution having film forming capability and skin substantivity which solution consists essentially of: (a) between 1 and 25 wt.% polyvinylpyrrolidone/iodine (PVP/I) complex; (b) between 5 and 15 wt.% vinylpyrrolidone/vinyl acetate copolymer (PVP/VA); (c) between 0.5 and 1.5 wt.% non-plasticizing polyethylene glycol (PEG); (d) between 35 and 75 wt.% C1 to C4 alkanol; (e) between 12 and 35 wt.% deionized water; and (f) between 0 and 2.5 wt.% of 1-vinyl-3-(E)-ethylidene pyrrolidone, based on total composition. The invention also relates to the method of preparing the film forming solution which has a drying time of less than 5 minutes.

Cette invention se rapporte à une solution complexe d'iode séchant rapidement, qui a la propriété de former un film et qui possède une affinité avec la peau, cette solution comprenant essentiellement: (a) entre 1 et 25 % en poids d'un complexe polyvinylpyrrolidone/iode (PVP/I); (b) entre 5 et 15 % en poids d'un copolymère vinylpyrrolidone/acétate de vinyl (PVP/AV); (c) entre 0,5 et 1,5 % en poids d'un polyéthylèneglycol (PEG) non plastifiant; (d) entre 35 et 75 % en poids d'un alcanol C¿1? à C¿4?; (e) entre 12 et 35 % en poids d'eau déionisée; et (f) entre 0 et 2,5 % en poids de 1-vinyl-3-(E)-éthylidène pyrrolidone, calculés sur la base de la composition totale. Cette invention se rapporte également au procédé de préparation de cette solution formant film, lequel se caractérise par un temps de séchage inférieur à 5 minutes.

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