Novel crystalline forms of a vegf-r inhibitor

Details Novel crystalline forms of a vegf-r inhibitor Novel crystalline forms of a vegf-r inhibitor

C - Chemistry, Metallurgy

07

D

C07D 401/06 (2006.01) A61K 31/4439 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2682859

The present invention relates to crystalline polymorphic and amorphous form of 6- [2- (methylcarbamoyl) phenyl sulfanyl] -3-E- [2- (pyridin-2- yl) ethenyl] indazole and to methods for their preparation. The invention is also directed to pharmaceutical compositions containing at least one polymorphic form and to the therapeutic or prophylactic use of such polymorphic forms and compositions.

La présente invention concerne une nouvelle forme cristalline polymorphe et amorphe de 6-[2-(méthyIcarbamoyl)phénylsulfanyl]-3-E-[2-(pyridin-2- yl)éthényl]indazole, et les procédés d'élaboration correspondant. L'invention concerne également des compositions pharmaceutiques contenant au moins une forme polymorphe et l'utilisation thérapeutique ou prophylactique de telles formes polymorphes et compositions.

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