Method for laminaribiose synthesis

C - Chemistry – Metallurgy – 07 – H

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C07H 3/06 (2006.01) C07H 17/04 (2006.01)

Patent

CA 2328289

The invention concerns a method for preparing Laminaribiose comprising a step for glycoside binding between a donor and an acceptor of glycosyl. The invention is characterised in that the glycosyl donor is in pyranose form and corresponds to formula (II); the glycosyl acceptor is in furanose form and corresponds to formula (III); said binding step is performed in solution in an anhydrous organic solvent, at a temperature ranging between -80 DEG C and 40 DEG C, for a time interval ranging between 1 minute and 8 hours, in the presence of a suitable promoter.

La présente invention concerne un procédé de préparation du Laminaribiose comprenant une étape de couplage glycosidique entre un donneur et un accepteur de glycosyle. Selon l'invention, le donneur de glycosyle se présente sous forme pyranosique et répond à la formule (II); l'accepteur de glycosyle se présente sous forme furanosique et répond à la formule (III); ladite étape de couplage est réalisée en solution dans un solvant organique anhydre, à une température comprise entre -80 °C et 40 °C, pendant une durée de 1 minute à 8 heures, en présence d'un promoteur approprié.

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