C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 14/715 (2006.01) C07K 16/28 (2006.01) C12N 15/10 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2365913
The present invention is directed to novel polypeptides having homology to members of the tumor necrosis factor receptor family and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
L'invention concerne des polypeptides qui présentent une homologie par rapport à la famille du récepteur de facteur de nécrose tumorale et des molécules d'acides nucléiques codant ces polypeptides. L'invention concerne également des vecteurs et des cellules hôtes renfermant les séquences d'acides nucléiques considérées, des molécules polypeptidiques chimères renfermant les polypeptides décrits en fusionnement avec des séquences polypeptidiques hétérologues, des anticorps qui se lient aux polypeptides décrits, et des procédés relatifs à l'élaboration desdits polypeptides.
Goddard Audrey
Pan James
Yan Minhong
Genentech Inc.
Smart & Biggar
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