Drug candidate selection by hydrogen exchange...

Details Drug candidate selection by hydrogen exchange... Drug candidate selection by hydrogen exchange...

A - Human Necessities

01

N

A01N 43/42 (2006.01)

Patent

CA 2572196

A method is provided of selecting a compound that (a) binds a receptor, and (b) on binding the receptor, induces a perturbation in the conformation of the receptor, which conformational perturbation is correlated with a particular pharmacological activity.

Procédé de sélection d'un médicament qui (a) se lie à un récepteur, et (b) au moment de sa liaison avec le récepteur, induit une perturbation dans la conformation du récepteur, laquelle perturbation est corrélée à une activité pharmacologique.

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