Isolated human drug-metabolizing proteins, nucleic acid...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/53 (2006.01) C07K 16/40 (2006.01) C12N 9/02 (2006.01)

Patent

CA 2426465

The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the drug-metabolizing enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the drug-metabolizing enzyme peptides, and methods of identifying modulators of the drug-metabolizing enzyme peptides.

L'invention concerne des séquences aminoacides de peptides qui sont codées par les gènes à l'intérieur du génome humain ainsi que les peptides enzymatiques métabolisant les médicaments. Cette invention porte plus particulièrement sur les molécules isolées de peptide et d'acide nucléique. Elle concerne également des méthodes permettant d'identifier les orthologues et les paralogues des peptides enzymatiques métabolisant les médicaments, ainsi que des méthodes permettant d'identifier les modulateurs des peptides enzymatiques métabolisant les médicaments.

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