Concurrent identification of multitudes of polypeptides

G - Physics – 01 – N

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G01N 33/68 (2006.01)

Patent

CA 2745197

Methods for sequencing a polypeptide and methods for structurally characterizing the polypeptide using labeled N-terminal amino acid specific complexing agents are disclosed. These methods relate to using arrays for identifying specific polypeptides of interest from a sample comprising multiple polypeptides. A method for identifying at least a portion of a polypeptide or protein of interest from a sample using N- terminal amino acid specific complexing agents is disclosed.

La présente invention concerne des procédés pour le séquençage dun polypeptide et des procédés pour caractériser structuralement le polypeptide en utilisant des agents de complexation dacide aminé spécifique à marquage N-terminal. Ces procédés concernent lutilisation de matrices pour identifier des polypeptides spécifiques dintérêt à partir dun échantillon comprenant des polypeptides multiples. La présente invention concerne en outre un procédé pour identifier au moins une portion dun polypeptide ou protéine dintérêt à partir dun échantillon en utilisant des agents de complexation dacide aminé spécifique N-terminal.

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