C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12N 5/16 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2315273
The present invention discloses the isolation and characterization of cDNA molecules encoding a novel member to the human nuclear receptor superfamily, designated nNR4. Also within the scope of the disclosure are recombinant vectors, recombinant host cells, methods of screening for modulators of nNR4 activity, and production of antibodies against nNR4, or epitopes thereof.
La présente invention concerne l'isolement et la caractérisation de molécules d'ADNc codant un nouveau membre de la superfamille des récepteurs nucléaires humains, à savoir nNR4. L'invention concerne également des vecteurs recombinés, des cellules hôtes recombinées, des méthodes de criblage de modulateurs de l'activité de nNR4, et la production d'anticorps contre nNR4, ou d'épitopes de ces anticorps.
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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