Chemical synthesis of 6-o-alkyl erythromycin a

Details Chemical synthesis of 6-o-alkyl erythromycin a Chemical synthesis of 6-o-alkyl erythromycin a

C - Chemistry, Metallurgy

07

H

C07H 17/08 (2006.01) A61K 31/7048 (2006.01)

Patent

CA 2309256

A process of preparing 6-O-alkyl erythromycin A is provided. The process includes the steps of protecting the oxime hydroxyl of 9-oxime erythromycin A with a benzoyl protecting group, protecting the 2'- hydroxyl group and optionally the 4'-hydroxyl group with an O-protecting group, alkylating the 6-hydroxyl, removing the benzoyl and O- protecting groups and deoximating the 9-oxime.

L'invention concerne un procédé de préparation de la 6-O-alkyl érythromycine A qui comprend les étapes suivantes: protection de l'oxime hydroxyle de la 9-oxime érythromycine A au moyen d'un groupe benzoyl; protection du groupe 2'-hydroxyle et, éventuellement, du groupe 4'-hydroxyle au moyen d'un groupe O; alkylation du 6-hydroxyle; élimination des groupes protecteurs benzoyl et O, et désoximation de la 9-oxime.

Affiliated with

Also associated with

Rating

Chemical synthesis of 6-o-alkyl erythromycin a does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chemical synthesis of 6-o-alkyl erythromycin a, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chemical synthesis of 6-o-alkyl erythromycin a will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1634724