Oxybutynin formulations and methods of use

A - Human Necessities – 61 – K

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A61K 47/12 (2006.01) A61K 31/215 (2006.01) A61K 31/216 (2006.01)

Patent

CA 2346332

Oxybutynin chloride formulations having increased stability at body temperature, even at high concentrations. These formulations comprise oxybutynin chloride at a pH of between 3.0 and 5.0, and may include a buffer capable of providing adequate buffering capacity in this range. The OC solutions can be placed in an infuser device for treatment of bladder dysfunction.

L'invention concerne des formulations de chlorure d'oxybutine ayant une stabilité accrue à la température du corps, même à des concentrations élevées. Lesdites formulations, qui sont constituées de chlorure à un pH situé entre 3,0 et 5,0, peuvent comprendre un tampon capable de fournir la capacité de tamponnage appropriée dans cet intervalle. Les solutions de chlorure d'oxybutine peuvent être placées dans un dispositif d'infusion destiné au traitement d'un dysfonctionnement vésical.

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