A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/047 (2006.01) A61K 31/13 (2006.01) A61K 31/7048 (2006.01) A61P 17/14 (2006.01) A61P 17/16 (2006.01)
Patent
CA 2741746
This invention regards the use of zeaxanthin and/or rutin, as such or further combined with spermidine, as the active principle in a pharmaceutical, dietary, or cosmetic composition, acting to inhibit caspase-3 and therefore to control apoptosis by preventing programmed cell death. The indication for this composition according to the invention is primarily the treatment of scalp disorders characterized by excessive cellular turnover including chemotherapy-induced alopecia, alopecia areata, androgenetic alopecia and telogen effluvium.
Cette invention porte sur l'utilisation de la zéaxanthine et/ou de la rutine, en tant que telles, ou combinées en outre avec de la spermidine, comme principe actif dans une composition pharmaceutique, alimentaire, ou cosmétique, agissant pour inhiber la caspase-3 et pour contrôler ainsi l'apoptose en prévenant la mort cellulaire programmée. Cette composition selon l'invention est principalement indiquée pour le traitement des troubles du cuir chevelu, caractérisés par une vitesse de renouvellement cellulaire excessive comprenant l'alopécie induite par une chimiothérapie, l'alopécie en aire, l'alopécie androgène et l'effluvium télogène.
Baroni Sergio
Benedusi Anna
Giuliani Giammaria
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Giuliani S.p.a.
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