A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/35 (2006.01) A61K 31/00 (2006.01) A61K 31/12 (2006.01) A61K 31/352 (2006.01) A61K 31/38 (2006.01) A61K 31/395 (2006.01)
Patent
CA 2321560
The present invention is directed to a method for the prophylactic and therapeutic treatment of diabetic retinopathy and a method for the prophylactic and therapeutic treatment of ocular inflammation. The methods involve the administration of an inhibitor of the protein tyrosine kinase pathway to an animal, such as a mammal, in particular a human, in an amount sufficient to treat diabetic retinopathy or ocular inflammation, respectively, prophylactically or therapeutically. The inhibitor of the protein tyrosine kinase pathway is preferably genistein or an analogue or prodrug thereof or a pharmaceutically acceptable salt of any of the foregoing.
La présente invention se rapporte à un traitement prophylactique et thérapeutique de la rétinopathie diabétique d'une part et des inflammations oculaires d'autre part. Ces traitements consistent à administrer à un animal tel qu'un mammifère, et notamment un humain, un inhibiteur du mécanisme des tyrosine-kinases en quantité suffisante pour le traitement prophylactique ou thérapeutique de la rétinopathie diabétique ou des inflammations oculaires. L'inhibiteur du mécanisme d'action des tyrosine-kinases est de préférence la génistéine, un analogue ou un précurseur de la génistéine, ou un sel, pharmaceutiquement acceptable, de génistéine ou de l'un de ses analogues ou précurseurs.
Johns Hopkins University School Of Medicine
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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