Process for preparing monobactames and their intermediate...

Details Process for preparing monobactames and their intermediate... Process for preparing monobactames and their intermediate...

C - Chemistry, Metallurgy

07

D

260/336

C07D 205/085 (2006.01)

Patent

CA 2022507

PROCESS FOR PREPARING MONOBACTAMES AND THEIR INTERMEDIATE PRODUCT ABSTRACT OF THE DISCLOSURE There is described a process for preparing monobactames of formula: Image where R = acyl, and their pharmaceutically acceptable salts, starting from ehyl (S)-3- hydroxybutanoate through the reaction intermediate (3S, 4R)-3- hydrazino-4-methyl-2-oxo-1-azetidine sulfonic acid or a salt thereof. This intermediate is new and therefore represents a further object of the present invention.

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