C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/26 (2006.01) C12N 5/12 (2006.01)
Patent
CA 2503708
A monoclonal antibody having high affinity for NT-proBNP is described. The monoclonal antibody is prepared against a synthetic peptide having the Sequence ID No. 1. The monoclonal antibody can be used as a reagent in an immunoassay system to identify blood, serum or plasma levels of NT-proBNP. Such an immunoassay system can be used for diagnosing and quantifying congestive heart failure.
L'invention concerne un anticorps monoclonal possédant une affinité élevée avec NT-proBNP. Cet anticorps monoclonal est préparé contre un peptide synthétique présentant la séquence ID No.1. L'anticorps monoclonal peut être utilisé en tant que réactif dans un système d'immuno-essai afin d'identifier les niveaux de sang, de sérum ou de plasma de NT-proBNP. Un tel système d'immuno-essai peut servir à diagnostiquer et à quantifier les insuffisances cardiaques congestives.
Gowling Lafleur Henderson Llp
Ottawa Heart Institute Research Corporation
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