Immunogenic cd19 ligand-antigenic molecule complexes and...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 19/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2515286

The present invention relates to complexes and fusion proteins comprising a CD91 ligand and an antigenic molecule, for use in the treatment or prevention of a disease. The invention specifically provides complexes comprising a CD91 ligand noncovalently boundto, or alternatively crosslinked to, an antigenic molecule. The invention also specifically provides fusion proteins comprising a CD91 ligand fused via a peptide bond to an antigenic molecule.

L'invention concerne des complexes et des protéines hybrides comportant un ligand CD91 et un molécule antigénique destinés au traitement ou à la prophylaxie d'une maladie. L'invention concerne particulièrement des complexes comportant un ligand CD91 lié par non-covalence ou alternativement réticulé à une molécule antigénique. L'invention concerne en outre des protéines hybrides comportant un ligand CD91 fixé au moyen d'une liaison peptidique sur un molécule antigénique.

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