Immunogenic acute phase protein-antigenic molecule complexes...

Details Immunogenic acute phase protein-antigenic molecule complexes... Immunogenic acute phase protein-antigenic molecule complexes...

A - Human Necessities

61

K

A61K 39/00 (2006.01)

Patent

CA 2515112

The present invention relates to complexes and fusion proteins comprising an acute phase protein and an antigenic molecule, for use in the treatment or prevention of a disease. The invention specifically provides for complexes comprising an acute phase protein noncovalently bound to, or alternatively crosslinked to, an antigenic molecule. The invention also specifically provides fusion proteins comprising an acute phase protein fused via a peptide bond to an antigenic molecule.

L'invention concerne des complexes et des protéines de fusion comprenant une protéine de phase aiguë et une molécule antigène utilisés pour traiter ou prévenir une maladie. De manière plus spécifique, l'invention concerne des complexes comprenant une protéine de phase aiguë liée de manière non covalente à une molécule antigène, ou alternativement réticulée avec celle-ci. L'invention concerne également des protéines de fusion comprenant une protéine de phase aiguë fusionnée via une liaison peptidique à une molécule antigène.

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