A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 49/00 (2006.01) A61K 31/404 (2006.01) A61K 31/4155 (2006.01) A61K 31/423 (2006.01) A61K 31/427 (2006.01) A61K 31/475 (2006.01) A61K 31/538 (2006.01)
Patent
CA 2657691
The presently disclosed subject matter provides compositions that selectively bind cyclooxygenase-2 and comprise a therapeutic and/or diagnostic moiety. Also provided are methods for using the disclosed compositions for diagnosing (i.e., by imaging) a target cell and/or treating a disorder associated with a cyclooxygenase-2 biological activity.
La présente invention a pour objet des compositions qui se lient de façon sélective à la cyclooxygénase-2 et qui comprennent une fonction thérapeutique et/ou diagnostique. La présente invention concerne également des méthodes d'emploi des compositions décrites dans le diagnostic (c'est-à-dire par imagerie) d'une cellule cible et/ou de traitement d'un trouble associé avec l'activité biologique d'une cyclooxygénase-2.
Crews Brenda C.
Marnett Lawrence J.
Uddin Jashim,
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Vanderbilt University
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