C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C12Q 1/48 (2006.01) C40B 40/06 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2533803
Biomarkers having expression patterns that correlate with a response of cells to treatment with one or more cdk modulating agents, and uses thereof. Also provided are methods for testing or predicting whether a mammal will respond therapeutically to a method of treating cancer that comprises administering an agent that modulates cdk activity.
L'invention concerne des biomarqueurs présentant des profils d'expression en corrélation avec une réponse de cellules à un traitement au moyen d'un ou de plusieurs agents modulant les cdk. Cette invention concerne également des utilisations desdits marqueurs ainsi que des méthodes pour tester ou prédire si un mammifère aura une réponse thérapeutique à une méthode de traitement du cancer consistant à administrer un agent modulant l'activité des cdk.
Jackson Donald G.
Li Martha
Rupnow Brent A.
Webster Kevin R.
Wong Tai W.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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