Antibodies to oncostatin m receptor

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) C12N 5/16 (2006.01) C12P 21/08 (2006.01) G01N 33/574 (2006.01) C07K 14/715 (2006.01)

Patent

CA 2597171

The invention provides characterization of the disease and cancer-associated antigen, OSM-R.beta. The invention also provides modulators of OSM-R.beta, including a family of monoclonal antibodies that bind to antigen OSM-R.beta, and methods of diagnosing and treating various human cancers and diseases associated with OSM-R.beta.

Cette invention concerne la caractérisation de l'antigène OSM-R.béta associé à la maladie et au cancer. Cette invention concerne également des modulateurs de OSM-R.béta, y compris une famille d'anticorps monoclonaux qui se lient à l'antigène OSM-R.béta ainsi que des méthodes de diagnostic et de traitement de différents cancers et maladies de l'homme associés à OSM-R.béta.

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