Pyrimidinyl aryl urea derivatives being fgf inhibitors

C - Chemistry – Metallurgy – 07 – D

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C07D 239/48 (2006.01) A61K 31/506 (2006.01)

Patent

CA 2634047

The invention relates to heteroaryl aryl ureas of the formula (IA), wherein the radicals and symbols have the meanings as defined herein, the use of such compounds in the treatment of protein kinase dependent diseases; to pharmaceutical preparations comprising said heteroaryl aryl ureas, to processes for the manufacture of such novel compounds and to methods of treatment comprising the use of such heteroaryl aryl ureas.

La présente invention concerne des hétéroaryle-arylurées représentés par la formule générale (IA). Dans cette formule, les radicaux et les symboles ont les significations définies dans la description. L'invention concerne également l'utilisation de tels composés pour le traitement d'affections en lien avec les protéine-kinases, des procédés de fabrication de tels composés de l'invention, et des procédés thérapeutique comprenant l'utilisation de telles hétéroaryle-arylurées.

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