Phenylthio acetic acid derivatives, process and intermediate...

C - Chemistry – Metallurgy – 07 – C

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C07C 327/22 (2006.01) A01N 37/50 (2006.01) C07C 327/12 (2006.01) C07C 327/38 (2006.01) C07D 213/60 (2006.01) C07D 237/08 (2006.01) C07D 239/24 (2006.01) C07D 241/10 (2006.01) C07D 251/12 (2006.01) C07D 261/06 (2006.01) C07D 263/30 (2006.01) C07D 275/02 (2006.01) C07D 277/20 (2006.01) C07D 307/34 (2006.01) C07D 333/04 (2006.01)

Patent

CA 2182406

Phenylthio acetic acid derivatives of formula (I) in which the components and index have the following meanings: R1 is hydrogen and alkyl; R2 is cyano, nitro, trifluoro methyl, halogen, alkyl and alkoxy; m is 0, 1 or 2, in which the radicals R2 may be different if m is 2; R3 is hydrogen, cyano, nitro, hydroxy, amino, halogen, alkyl, halogen alkyl, alkoxy, halogen alkoxy, alkylthio, alkylamino or dialkylamino; R4 is hydrogen, cyano, nitro, hydroxy, amino, halogen, possibly substituted alkyl, alkoxy, alkylthio, alkylamino, dialkylamino, alkenyl, alkenyloxy, alkenylthio, alkenylamino, N-alkenyl-N- alkylamino, alkinyl, alkinyloxy, alkinylthio, alkinylamino, N-alkinyl-N- alkylamino, possibly substituted cycloalkyl, cycloalkyloxy, cycloalkylthio, cycloalkylamino, N-cycloalkyl-N-alkylamino, cycloalkenyl, cycloalkenyloxy, cycloalkenylthio, cycloalkenylamino, N-cycloalkenyl-N-alkylamino, heterocyclyl, heterocyclyloxy, heterocyclylthio, heterocyclylamino, N- heterocyclyl-N-alkylamino, aryl, aryloxy, arylthio, arylamino, N-aryl-N- alkylamino, hetaryl, hetaryloxy, hetarylthio, hetarylamino, N-hetaryl-N- alkylamino; R5 is hydrogen, possibly substituted alkyl, cycloalkyl, alkenyl, alkinyl, alkyl carbonyl, alkenyl carbonyl, alkinyl carbonyl or alkyl sulphonyl, possibly substituted aryl, aryl carbonyl, aryl sulphonyl, hetaryl, hetaryl carbonyl or hetaryl sulphonyl. The invention also concern their salts, the process and intermediate products for their production and their use.

L'invention concerne des dérivés d'acide phénylacétique de la formule (I) dans laquelle les substituants et l'indice ont la notation suivante: R?1¿ désigne hydrogène et alkyle; R?2¿ désigne cyano, nitro, trifluorométhyle, halogène, alkyle et alcoxy; m vaut 0, 1 ou 2, les restes R?2¿ pouvant être différents, si m vaut 2; R?3¿ désigne hydrogène, cyano, nitro, hydroxy, amino, halogène, alkyle, halogénure d'alkyle, alcoxy, halogénure d'alcoxy, alkylthio, alkylamino ou dialkylamino; R?4¿ désigne hydrogène, cyano, nitro, hydroxy, amino, halogène, alkyle éventuellement substitué, alcoxy, alkylthio, alkylamino, dialkylamino, alcényle, alcényloxy, alcénylthio, alcénylamino, N-alcényl-N-alkylamino, alkinyle, alkinyloxy, alkinylthio, alkinylamino, N-alkinyl-N-alylamino, cycloalkyle éventuellement substitué, cycloalkyloxy, cycloalkylthio, cycloalkylamino, N-cycloalkyl-N-alkylamino, cycloalcényle, cycloalcényloxy, cycloalcénylthio, cycloalcénylamino, N-cycloalcényl-N-alkylamino, hétérocyclyle, hétérocyclyloxy, hétérocyclylthio, hétérocyclylamino, N-hétérocyclyl-N-alkylamino, aryle, aryloxy, arylthio, arylamino, N-aryl-N-alkylamino, hétaryle, hétaryloxy, hétarylthio, hétarylamino, N-hétaryl-N-alkylamino; R?5¿ désigne hydrogène, alkyle éventuellement substitué, cycloalkyle, alcényle, alkinyle, alkylcarbonyle, alcénylcarbonyle, alkinylcarbonyle ou alkylsulfonyle, aryle éventuellement substitué, arylcarbonyle, arylsulfonyle, hétaryle, hétarylcarbonyle ou hétarylsulfonyle. L'invention concerne par ailleurs leurs sels, leur procédé de préparation, les produits intermédiaires utilisés à cet effet, et leur utilisation.

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