Optical imaging agents

Details Optical imaging agents Optical imaging agents

A - Human Necessities

61

K

A61K 49/00 (2006.01)

Patent

CA 2755770

The present invention relates to a method of in vivo optical imaging, of the margins around tumours, which com-prises an optical imaging contrast agent. The optical imaging agents comprise conjugates of near-infrared dyes with synthetic polyethyleneglycol (PEG) polymers having a molecular weight in the range 15-45 kDa. Also disclosed are optical imaging con-trast agents, pharmaceutical compositions and kits.

La présente invention concerne un procédé qui permet d'effectuer l'imagerie optique in vivo, des bordures entourant les tumeurs, reposant sur l'utilisation d'un agent de contraste d'imagerie optique. Les agents d'imagerie optique comprennent des conjugués de colorants dans l'infrarouge proche et de polymères synthétiques de polyéthylèneglycol (PEG) ayant un poids moléculaire compris entre 15 et 45 kDa. La présente invention concerne en outre des agents de contraste d'imagerie optique, des compositions pharmaceutiques et des kits.

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