Dimetalhydroxy malates

Details Dimetalhydroxy malates Dimetalhydroxy malates

A - Human Necessities

61

K

A61K 33/06 (2006.01) A23K 1/175 (2006.01) A23L 1/304 (2006.01) A61K 31/194 (2006.01) A61K 33/00 (2006.01) A61K 33/30 (2006.01) A61P 3/02 (2006.01)

Patent

CA 2508180

Dimetalhydroxy malate compositions as well as methods of administering and making such bioavailable compositions are provided. The metal used can be any nutritionally relevant divalent metal such as calcium, magnesium, zinc, copper, manganese, and iron. The composition can be prepared by reacting malic acid with a divalent metal oxide or hydroxide at a 1:2 molar ratio. The composition can be administered to a warm-blooded animal by any of a number of known delivery routes, including oral delivery.

Cette invention concerne des compositions de malate de dimétalhydroxy malate ainsi que des méthodes d'administration et de fabrication de ces compositions biodisponibles. Le métal utilisé peut être n'importe quel métal divalent convenant à des fins nutritionnelles tel que calcium, magnésium, zinc, cuivre, manganèse et fer. On peut obtenir cette composition par réaction d'un acide malique avec un oxyde ou un hydroxyde de métal divalent selon un rapport molaire de 1:2. La composition peut être administrée à un animal à sang chaud par l'une quelconque des voies connues d'administration, per os notamment.

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