Methods for modulating fxr receptor activity

A - Human Necessities – 61 – K

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A61K 31/695 (2006.01) A61K 31/551 (2006.01) A61K 31/553 (2006.01) A61K 31/554 (2006.01) A61P 9/10 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2377320

Methods for modulating the activity of the mammalian FXR receptor. The methods include methods of treating a hyper- or hypocholesterolemic mammal comprising contacting the mammal with synthetic compounds having FXR receptor activity.

L'invention concerne des procédés permettant de moduler l'activité du récepteur FXR mammalien, y compris des procédés pour le traitement d'un mammifère hypercholestérolémique ou hypocholestérolémique, consistant à mettre le mammifère en contact avec des composés synthétiques à activité de récepteur FXR.

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