Repression of cell transformation with human pea3

Details Repression of cell transformation with human pea3 Repression of cell transformation with human pea3

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2332634

The present invention relates generally to the fields of cancer therapy and gene therapy. More particularly, it demonstrates that PEA3, as exemplified by mPEA3, and hPEA3, is a tumor suppressor and may be used to treat various forms of cancer, for example neu- or ras--mediated cancers.

L'invention concerne d'une manière générale les domaines de la thérapie anticancéreuse et de la thérapie génique. Plus particulièrement, on s'est aperçu que la protéine PEA3 (par exemple mPEA3 et hPEA3), avait un effet suppresseur de tumeur et pouvait être utilisée pour traiter diverses formes de cancer, comme les cancers à médiation assurée par neu ou ras.

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