Solid drug for oral use

Details Solid drug for oral use Solid drug for oral use

A - Human Necessities

61

K

A61K 31/4045 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 9/48 (2006.01) A61K 45/00 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01) A61P 13/00 (2006.01) A61P 13/02 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2507002

It is intended to provide a solid drug to be orally used for treating urinary disturbance which contains an indoline compound having an .alpha.1-adrenaline receptor blocking effect and being represented by the following formula: its prodrug, a pharmacologically acceptable salt thereof or a pharmacologically acceptable solvate thereof, and is prepared so as to show an 85% elution time of not longer than 60 minutes in the elution test in water in accordance with the second elution test method (the paddle method) in Japan Pharmacopoeia.

L'invention concerne un médicament solide administré par voie orale dans le traitement des troubles urinaires, contenant un composé d'indoline présentant un effet de blocage du récepteur de l'adrénaline .alpha.¿1? et étant représenté par la formule suivante, son promédicament, un sel acceptable d'un point de vue pharmacologique de celui-ci ou un solvate acceptable d'un point de vue pharmacologique de celui-ci, et préparé de manière à présenter un temps d'élution à 85 % ne dépassant pas 60 minutes dans le test d'élution dans l'eau selon la méthode du second test d'élution (méthode utilisant un appareil à palette) de la pharmacopée japonaise.

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