Compositions and methods relating to heat shock...

Details Compositions and methods relating to heat shock... Compositions and methods relating to heat shock...

A - Human Necessities

61

K

A61K 31/415 (2006.01) A61K 31/4155 (2006.01) A61K 31/426 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2724413

The present invention relates to HSF activating compounds, methods for their discovery, and their research and therapeutic uses. In particular, the present invention provides compounds capable of facilitating HSF1 activation, and methods of using such compounds as therapeutic agents to treat a number of conditions associated with protein misfolding.

La présente invention concerne des composés activant le HSF, des procédés pour leur découverte, et leur recherche et leurs utilisations thérapeutiques. En particulier, la présente invention concerne des composés capables de faciliter lactivation du HSFl, et des procédés destinés à utiliser de tels composés en tant quagents thérapeutiques afin de traiter plusieurs états pathologiques associés au mauvais repliement des protéines.

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