Novel substituted imidazoquinolines

Details Novel substituted imidazoquinolines Novel substituted imidazoquinolines

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4745 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2719544

Imidazoquinolines of formula I that contain substituted amine or amide functionality at 1- position and that are ef-fective as Toll like Receptor 7 activators are disclosed. These compounds are useful as anticancer agents.

La présente invention concerne des imidazoquinolines de formule I qui contiennent une fonctionnalité amine ou amide substituée à la position 1 et qui sont efficaces en tant quactivateurs de récepteurs de type Toll 7. Ces composés sont utiles en tant quagents anticancéreux.

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