C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/4178 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2426337
This invention relates to substituted imidazoles of Formula I, pharmaceutical compositons containing them, methods of using them and intermediates useful in their manufacture. The compounds of the invention modulate the production of a number of inflammatory cytokines and are useful in the treatment of diseases associated with the overpopulation of inflammatory cytokines.
L'invention concerne des imidazoles substitués de formule (I), des compositions pharmaceutiques les renfermant, des procédés mettant en oeuvre celles-ci, ainsi que des produits intermédiaires utilisés dans leur fabrication. Les composés selon l'invention modulent la production d'une pluralité de cytokines inflammatoires et sont utilisés dans le traitement de maladies associées à une surproduction de cytokines inflammatoires.
Beers Scott
Wachter Michael P.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Ortho-Mcneil Pharmaceutical Inc.
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