Glucoamylase promoter obtained from neurospora crassa and...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/80 (2006.01) C12N 1/15 (2006.01) C12N 9/34 (2006.01) C12N 15/11 (2006.01) C12N 15/56 (2006.01) C12P 21/00 (2006.01)

Patent

CA 2169377

The invention relates to a method and recombinant means for engineering the production of heterologous peptides in filamentous fungus. The invention involves the genetic manipulation of the glucoamylase gene in order to provide a restriction site in same so that the promoter sequence of said gene can be coupled to a heterologous peptide whereby the production of said peptide will be under the control of the promoter sequence of the glucoamylase gene.

L'invention se rapporte à un procédé et à des moyens recombinants destinés à l'organisation de la production de peptides hétérologues chez le champignon filamenteux. Cette invention comporte la manipulation génétique du gène de glucoamylase de manière à y pourvoir un site de restriction, afin que la séquence promotrice dudit gène puisse être couplée à un peptide hétérologue, permettant ainsi que la production dudit peptide soit sous le contrôle de la séquence promotrice du gène de glucoamylase.

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