A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 8/33 (2006.01) A61K 8/40 (2006.01) A61Q 13/00 (2006.01)
Patent
CA 2731965
Disclosed is a stock solution of coolant materials for use in formulating consumer products comprising at least about 5% of one or a mixture of menthane carboxamide coolant materials and a solvent having individual Hansen solubility parameters of a dispersion force component (deltaD) ranging from about 15.2 to 21.2 (MPa) 0.5, a polar component (deltaP) ranging from about 0 to 10.8 (MPa) 0.5 and a hydrogen bonding component (deltaH) ranging from about 0 to 19.1 (MPa) 0.5. Preferably the menthane carboxamide is N-(4-cyanomethyl)phenyl-2-isopropyl-5- methylcyclohexanecarboxamide and the solvent is selected from benzaldehyde, benzyl alcohol, benzyl salicylate, alpha amyl cinnamic aldhehyde, cuminylaldehyde, para-Tolualdehyde, 2,5-dimethyl Pyrazine, 2,3-dimethyl Pyrazine, neryl acetate, isoamyl propionate, menthone, carvacrol, propyl acetate, 2-ethylhexyl acetate, bornyl acetate, butyl acetate, dimethal benzyl carbinol acetate, cis- hexenyl acetate, trans-hexenyl acetate, menthyl acetate, isopulegol, ethyl amyl ketone, parcresyl methyl ether, ethyl oenanthate, isobutyl salicylate, terpinolene, geranyl acetate, hexyl acetate and dipentene.
L'invention porte sur une solution mère de divers réfrigérants, destinée à la préparation de produits de consommation comprenant au moins environ 5% de réfrigérants carboxamide de menthane ou d'un solvant ou un mélange de ces composés, le solvant possédant des paramètres de solubilité Hansen individuels d'un composant de force de dispersion (deltaD) compris entre 15.2 et 21.2 (MPa) environ, un composant polaire (deltaP) compris entre 0 et 10.8 (MPa) environ et un composant de liaison à l'hydrogène (deltaH) compris entre 0 et 19.1 (MPa) environ. De préférence le carboxamide de menthane est N- (4-cyanométhyl)phényl-2-isopropyl-5-méthylcyclohexanecarboxamide et le solvant est sélectionné parmi benzaldehyde, alcool benzyle, benzyle salicylate, alpha amyle, aldhéhyde cinnamique, cuminylaldehyde, para-Tolualdehyde, 2, 5-diméthyl Pyrazine, 2,3-diméthyl Pyrazine, néryl acétate, isoamyl propionate, menthone, carvacrol, propyl acétate, 2-ethylhexyl acétate, bornyl acétate, butyl acétate, diméthal benzyl carbinol acétate, cis-hexényl acétate, trans-hexényl acétate, menthyl acétate, isopulegol, ethyl amyl cétone, parcrésyl méthyl éther, éthyl oenanthate, isobutyl salicylate, terpinolène, géranyl acétate, hexyl acétate et dipentène.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
The Procter & Gamble Company
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