Immunoregulatory agents

Details Immunoregulatory agents Immunoregulatory agents

A - Human Necessities

61

K

167/237

A61K 31/415 (2006.01)

Patent

CA 2019996

Abstract of the Disclosure Specific aspects of the cellular and humoral immune systems of a mammalian host are regulated by administering to the host a compound having a reactive immunoregulatory conformation whose precise three-dimensional structure is defined herein. Sorbinil, tolrestat, WF-3681, and the other immunoregulatory agents described herein possess this reactive conformation and so are therapeutically useful for inhibiting delayed-type hypersensitivity, T-cell proliferation, and B-cell antibody production, without altering the normal cellularity of the immune system or the normal metabolites of the arachidonic acid pathway.

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