Substituted imides as tnf inhibitors

Details Substituted imides as tnf inhibitors Substituted imides as tnf inhibitors

C - Chemistry, Metallurgy

07

D

C07D 209/44 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) C07D 207/26 (2006.01) C07D 207/40 (2006.01) C07D 209/46 (2006.01) C07D 209/48 (2006.01) C07D 211/76 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01)

Patent

CA 2208671

Novel imides of the general formula (see above formula) are inhibitors of tumor necrosis factor alpha and can be used to combat cachexia, endotoxic shock, and retrovirus replication. A typical embodiment is 2- Phthalimido- 3-(3',4'-dimethoxyphenyl)propane.

Des imides nouveaux inhibent le facteur alpha de nécrose tumorale et sont utiles pour combattre la cachexie, le choc endotoxique et la réplication rétrovirale. Un mode de réalisation typique est le 2-phtalimido-3-(3',4'-diméthoxyphényl)propane.

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