Proteases from gram-positive organisms

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/57 (2006.01) A23K 1/165 (2006.01) C11D 3/386 (2006.01) C12N 1/20 (2006.01) C12N 1/21 (2006.01) C12N 9/56 (2006.01) C12N 15/75 (2006.01) C12Q 1/68 (2006.01) D06M 16/00 (2006.01)

Patent

CA 2272048

The present invention relates to the identification of novel metallo-proteases (MP) in Gram-positive microorganisms. The present invention provides the nucleic acid and amino acid sequences for Bacillus (MP). The present invention also provides host cells having mutation or deletion of part or all of the gene encoding MP. The present invention also provides host cells further comprising nucleic acid encoding desired heterologous proteins such as enzymes. The present invention also provides cleaning compositions comprising an MP of the present invention.

La présente invention se rapporte à l'identification de nouvelles métalloprotéases (MP) dans des organismes gram positifs. Elle se rapporte à des séquences d'acides nucléiques et d'acides aminés associées à Bacillus (MP) ainsi qu'à des cellules hôtes possédant une mutation ou une délétion de tout ou partie du gène codant MP. La présente invention se rapporte également à des cellules hôtes comportant en outre un acide nucléique codant des protéines hétérologues telles que des enzymes. Enfin, cette invention se rapporte à des compositions détergentes comportant une métalloprotéase telle que celles décrites ci-dessus.

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