Sustained release heterodisperse hydrogel systems -...

Details Sustained release heterodisperse hydrogel systems -... Sustained release heterodisperse hydrogel systems -...

A - Human Necessities

61

K

A61K 9/22 (2006.01) A61K 9/20 (2006.01) A61K 31/455 (2006.01) C08J 3/075 (2006.01)

Patent

CA 2251816

Sustained release oral solid dosage forms comprising agglomerated particles of a therapeutically active medicament in amorphous form, a gelling agent, an ionizable gel strength enhancing agent and an inert diluent, as well as processes for preparing and using the same are disclosed. The sustained release oral solid dosage forms are useful in the treatment of hypertension in human patients.

L'invention se rapporte à des dosages galéniques solides, s'administrant par voie orale, à libération prolongée qui comprennent des particules agglomérées d'un médicament thérapeutiquement actif, de forme amorphe, un agent gélifiant, un agent renforçant la solidité du gel ionisable et un diluant inerte, ainsi qu'à des procédés de préparation et d'utilisation de ceux-ci. Ces dosages galéniques sont utilisés dans le traitement de l'hypertension chez l'homme.

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