C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/09 (2006.01) A61K 35/76 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01) A61P 13/08 (2006.01) A61P 13/10 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01) C07K 7/06 (2006.01) C12Q 1/02 (2006.01) A61K 35/26 (2006.01) C12N 5/06 (2006.01)
Patent
CA 2638122
Disclosed are: a peptide comprising an amino acid sequence composed of contiguous nine amino acid residues derived from a WT1 protein, wherein an amino acid residue at position 2 in the amino acid sequence is selected from the group consisting of Ala, Ile, Leu, Val, Phe, Tyr, Ser and Asp and an amino acid residue at position 9 in the amino acid sequence is Arg; a polynucleotide encoding the peptide; a pharmaceutical composition comprising the peptide; and others.
La présente invention concerne : un peptide comprenant une séquence d'acides aminés composée de neuf résidus contigus d'acides aminés dérivés d'une protéine WT1, où un résidu d'acides aminés en position 2 de la séquence d'acides aminés est sélectionné parmi le groupe composé de Ala, Ile, Leu, Val, Phe, Tyr, Ser et Asp et un résidu d'acides aminés en position 9 de la séquence d'acides aminés est Arg; un polynucléotide codant pour le peptide; une composition pharmaceutique comprenant le peptide; ainsi que d'autres éléments.
International Institute Of Cancer Immunology Inc.
Kirby Eades Gale Baker
LandOfFree
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