A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/05 (2006.01) A61K 31/195 (2006.01) A61K 31/198 (2006.01) A61K 38/06 (2006.01) A61K 38/55 (2006.01) A61P 9/10 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2350133
The present invention relates to a method for treating tissue damage caused by ischemia in a patient which comprises administering to said patient a therapeutically effective amount of a compound which is an inhibitor of cathepsin B or cathepsin L, but which is not as an effective inhibitor of calpain relative to cathepsin B or cathepsin L or both and which compound is a peptidyl diazomethyl ketone.
La présente invention concerne un traitement de tissus ischémiquement dégradés chez un patient comprenant l'administration audit patient d'une dose térapeutiquement efficace d'un composé qui est un inhibiteur des cathepsines B ou L, mais qui n'est pas un inhibiteur aussi efficace des calpaïnes que l'une et/ou l'autre des deux enzymes précitées. Ce composé est une peptidyle-diazométhylecétone.
Anagli John
Seyfried Donald M.
Mcfadden Fincham
Research Corporation Technologies Inc.
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