Iminopyrimidine nmda nr2b receptor antagonists

Details Iminopyrimidine nmda nr2b receptor antagonists Iminopyrimidine nmda nr2b receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 239/42 (2006.01) A61K 31/505 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) C07D 239/70 (2006.01) C07D 471/04 (2006.01) C07D 487/00 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2412640

Compounds described by the chemical structural formula (I) or a pharmaceutically acceptable salt thereof, are useful in the treatment of pain, migraine, depression, anxiety, schizophrenia, Parkinson's disease, stroke, and in the treatment of neuropathies including postherpetic neuralgia, central pain from spinal cord injury, and phantom limb pain.

L'invention concerne des composés représentés par la formule structurale chimique (I) ou un sel pharmaceutiquement acceptable desdits composés, qui sont utilisés dans le traitement de la douleur, de la migraine, de la dépression, de l'anxiété, de la schizophrénie, de la maladie de Parkinson, des accidents vasculaires cérébraux ainsi que dans le traitement des neuropathies, notamment l'algie post-zotérienne, les douleurs centrales liées à une lésion de moelle épinière et la douleur du membre fantôme.

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