Novel carboxyalkyl derivatives useful as inhibitors of...

Details Novel carboxyalkyl derivatives useful as inhibitors of... Novel carboxyalkyl derivatives useful as inhibitors of...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/55 (2006.01) C07D 487/04 (2006.01) C07D 491/147 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2078759

The present invention relates to compounds of the formula (see Formula I) wherein B1 and B2 are each independently hydrogen; hydroxy; -OR2 wherein R2 is a C1-C4 alkyl or an Ar-Y group wherein Ar is aryl and Y is a hydrogen or C1-C4 alkyl; or, where B1 and B2 are attached to adjacent carbon atoms, B1 and B2 can be taken together with said adjacent carbons to form a benzene ring or methylenedioxy; A is a bond, methylene or oxygen, sulfur or NR4 or NCOR5 wherein R4 is hydrogen, a C1-C4 alkyl or an Ar-Y- group and R5 is -CF3, a C1-C10 alkyl or an Ar-Y- group; R3 is hydrogen or -CH2OC(O)C(CH3)3; R1 is hydrogen, C1-C4 alkyl or -CH2OC(O)-C(CH3)3; and n is an integer 1 to 3, which are useful as inhibitors of enkephalinase and ACE.

Affiliated with

Also associated with

Rating

Novel carboxyalkyl derivatives useful as inhibitors of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel carboxyalkyl derivatives useful as inhibitors of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel carboxyalkyl derivatives useful as inhibitors of... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1645660