Process for forming clear, wettable silicone hydrogel articles

G - Physics – 02 – B

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G02B 1/04 (2006.01) B29D 11/00 (2006.01)

Patent

CA 2668156

The present invention is a process for forming ophthalmic devices such as contact lenses, comprising the steps of curing a reactive mixture comprising at least one silicone-containing component, at least one hydrophilic component and at least one protonated diluent or protonatable diluent having a Hansen solubility parameter, .delta.p between about 2 and about 7 to form an ophthalmic device having an advancing contact angle of less than about 80°; contacting the ophthalmic device with an aqueous solution which is capable of changing the Hansen solubility parameter, .delta.p of the protonated or protonatable co-diluent to enhance water solubility and removing said diluent(s) with said aqueous solution.

La présente invention concerne un procédé destiné à former des dispositifs ophtalmiques tels que des lentilles de contact, comprenant les étapes consistant à : faire durcir un mélange réactif comprenant au moins un composant contenant de la silicone, au moins un composant hydrophile et au moins un diluant protoné ou un diluant protonable présentant un paramètre de solubilité de Hansen (.delta.p) compris entre environ 2 et environ 7, afin de former un dispositif ophtalmique présentant un angle de contact avançant inférieur à environ 80 °; mettre le dispositif ophtalmique en contact avec une solution aqueuse qui est susceptible de modifier le paramètre de solubilité de Hansen (.delta.p) du co-diluant protoné ou protonable afin d'améliorer la solubilité dans l'eau, et éliminer le(s)dit(s) diluant(s) à l'aide de ladite solution aqueuse.

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