Diphenyl pyridyl ethane derivatives as pde iv inhibitors

Details Diphenyl pyridyl ethane derivatives as pde iv inhibitors Diphenyl pyridyl ethane derivatives as pde iv inhibitors

C - Chemistry, Metallurgy

07

D

C07D 213/30 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/4409 (2006.01) A61K 31/4439 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61P 11/06 (2006.01) A61P 29/00 (2006.01) A61P 43/00 (2006.01) C07D 213/44 (2006.01) C07D 213/50 (2006.01) C07D 213/53 (2006.01) C07D 213/60 (2006.01) C07D 213/89 (2006.01) C07D 233/54 (2006.01) C07D 401/10 (2006.01) C07D 403/10 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2239053

The invention encompasses the novel compound of formula (I) useful in the treatment of diseases, including asthma, by raising the level of cyclic adenosine-3',5'-monophosphate (cAMP) through the inhibition of phosphodiesterase IV (PDE IV). The invention also encompasses certain pharmaceutical compositions and methods for treatment of diseases by inhibition of PDE IV, resulting in an elevation of cAMP, comprising the use of compounds of formula (I).

Nouveau composé de formule (I) utilisé pour traiter des maladies, y compris l'asthme, par augmentation du niveau d'adénosine-3',5'-monophosphate cyclique (cAMP), cette augmentation étant obtenue par l'inhibition de la phosphodiestérase IV (PDE IV). L'invention se rapporte également à certaines compositions pharmaceutiques et à des méthodes de traitement des maladies par inhibition de la PDE IV, entraînant une augmentation de cAMP, ces méthodes consistant à utiliser des composés de la formule (I).

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