Compstatin and analogs thereof for eye disorders

Details Compstatin and analogs thereof for eye disorders Compstatin and analogs thereof for eye disorders

A - Human Necessities

61

K

A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2625206

The present invention features the use of compstatin and complement inhibiting analogs thereof for treating and/or preventing age related macular degeneration and other conditions involving macular degeneration, choroidal neovascularization, and/or retinal neovascularization. The invention also provides compositions comprising compstatin or a complement inhibiting analog thereof and a second therapeutic agent. The invention also provides compositions comprising compstatin or a complement inhibiting analog thereof and a gel-forming material, e.g., soluble collagen, and methods of administering the compositions.

La présente invention concerne l'utilisation de compstatine et d'analogues inhibiteurs de complément de celle-ci pour traiter et/ou prévenir la dégénérescence maculaire liée à l'âge et d'autres affections impliquant une dégénérescence maculaire, une néovascularisation choroïdienne et/ou une néovascularisation rétinienne. L'invention concerne également des compositions comprenant de la compstatine ou un analogue inhibiteur de complément de celle-ci et un second agent thérapeutique. L'invention concerne également des compositions comprenant de la compstatine ou un analogue inhibiteur de complément de celle-ci et une matière formant un gel, par exemple du collagène soluble, et des procédés d'administration des compositions.

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