C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 473/06 (2006.01) A61K 31/52 (2006.01) A61K 31/522 (2006.01) A61P 3/10 (2006.01) C07D 473/00 (2006.01) C07D 473/04 (2006.01) C07D 473/08 (2006.01)
Patent
CA 2411864
The present invention relates to therapeutically active and selective inhibitors of the enzyme DPP-IV, pharmaceutical compositions comprising the compounds and the use of such compounds for and the manufacture of medicaments for treating diseases that are associated with proteins which are subject to inactivation by DPP-IV, such as type 2 diabetes and obesity, as well as methods for treating diseases that are associated with proteins which are subject to inactivation by DPP-IV, such as type 2 diabetes and obesity.
La présente invention concerne des inhibiteurs sélectifs, thérapeutiquement actifs, de l'enzyme DPP-IV, des compositions pharmaceutiques renfermant lesdits composés et l'utilisation de ces derniers pour la fabrication de médicaments utilisés dans le traitement de maladies associées à des protéines soumises à l'inactivation par l'enzyme DPP-IV, telles que le diabète de type 2 et l'obésité. L'invention concerne également des méthodes de traitement de pathologies associées à des protéines soumises à l'inactivation par l'enzyme DPP-IV, telles que le diabète de type 2 ou l'obésité.
Christiansen Lise Brown
Kanstrup Anders Bendtz
Kristiansen Marit
Lundbeck Jane Marie
Sams Christian K.
Dimock Stratton Llp
Novo Nordisk A/s
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