Use of nitric oxide donor and/or substrate for inducing...

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/19 (2006.01) A61K 31/04 (2006.01) A61K 31/155 (2006.01) A61K 31/195 (2006.01) A61K 31/198 (2006.01) A61K 31/21 (2006.01) A61K 31/223 (2006.01) A61K 31/295 (2006.01) A61K 31/34 (2006.01) A61K 31/557 (2006.01) A61K 31/56 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2214779

The invention describes the regulation of cervical dilatation and extensibility by the use of nitric oxide donors and/or substrates or nitric oxide inhibitors. There can be used either (a) at least one nitric oxide donor and/or substrate for manufacture of a medicament to be administered locally intracervically or intravaginally for induction of cervical ripening or (b) at least one nitric oxide inhibitor for manufacture of a medicament to be administered locally intracervically or intravaginally for treatment of cervical insufficiency or preterm labor.

Cette invention concerne un procédé permettant de modifier la dilatation et l'extensibilité cervicales grâce à l'emploi de donneurs et/ou de substrats d'oxyde d'azote ou d'inhibiteurs d'oxyde azote. On peut utiliser à cette fin (a) soit au moins un donneur et/ou substrat d'oxyde d'azote afin de fabriquer un médicament qui sera administré localement par voie intracervicale ou intravaginale afin de déclencher le mûrissement cervical, (b) soit au moins un inhibiteur d'oxyde d'azote afin de fabriquer un médicament qui sera administré localement par voie intracervicale ou intravaginale afin de traiter une insuffisance cervicale ou un travail préterme.

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