Improved pharmaceutical composition comprising fenofibrate

Details Improved pharmaceutical composition comprising fenofibrate Improved pharmaceutical composition comprising fenofibrate

A - Human Necessities

61

K

A61K 31/21 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 31/216 (2006.01)

Patent

CA 2214895

The bioavailability of fenofibrate is improved by making a solid dispersion of adisentegrant in the fenofibrate. Method of making said solid dispersion comprising melting the fenofibrate, blending the disintegrant into the melt, and resolidifying the mixture.

Amélioration de la biodisponibilité du fénofibrate par la production d'une dispersion solide d'un délitant dans le fénofibrate. La méthode de production d'une telle dispersion solide consiste à faire fondre le fénofibrate, à mélanger le délitant dans le produit fondu et à resolidifier le mélange.

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