Pyrazolo [3, 4 -d] pyrimidine p38 map kinase inhibitors

Details Pyrazolo [3, 4 -d] pyrimidine p38 map kinase inhibitors Pyrazolo [3, 4 -d] pyrimidine p38 map kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/517 (2006.01) A61P 1/00 (2006.01) A61P 7/00 (2006.01) A61P 19/02 (2006.01)

Patent

CA 2672719

Compounds of formula Ia or Ib: wherein R1, R2, R3 and R4 are as defined herein. Also disclosed are methods of making 5 the compounds and methods of using the compounds for treatment of p38 MAP kinase-mediated diseases.

L'invention concerne des composés de formule Ia ou Ib : dans lesquelles R1, R2, R3 et R4 sont tels que définis présentement. L'invention concerne également des procédés de fabrication des composés et des procédés d'utilisation des composés pour le traitement de maladies à médiation par la P38 MAP kinase.

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