A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/19 (2006.01) A61K 31/194 (2006.01) A61K 31/38 (2006.01)
Patent
CA 2366073
The invention relates to the use of succinic acid or pharmaceutically acceptable salts thereof for manufacture of medicaments or nutritional supplements effective for treating of insulin resistance in mammals, preferably in a non-insulin dependent diabetic humans. Insulin resistance is associated with disorders such as diabetes mellitus and its chronic complications such as retinopathy, polyneuropathy, nephrophathy, angiopathy, gestational diabetes mellitus; impaired glucose tolerance; obesity; aging; atherosclerosis; syndrome X; cardiovascular disease; AIDS; cancer; wasting/cachecxia; sepsis; trauma associated with burns; malnutrition; lupus and other autoimmune diseases; endocrine diseases; hyperuricemia; hyperlipidemia; dyslipidemia; polycystic ovary syndrome or complications arising from athletic activity. The invention provides a method of treating insulin resistance in mammals, preferably, in humans, which comprises administering to a mammal in need thereof succinic acid or pharmaceutically acceptable salts thereof.
Cette invention concerne l'utilisation de l'acide succinique ou de sels de cet acide acceptables au plan pharmaceutique pour la fabrication de médicaments ou de compléments nutritionnels efficaces pour le traitement de l'insulino-résistance chez des mammifères, de préférence chez des humains diabétiques non insulino-dépendants. L'insulino-résistance est associée à des troubles tels que le diabète sucré et ses complications chroniques, à savoir notamment rétinopathie, polyneuropathlie, néphropathie, angiopathie, diabète sucré de la grossesse, tolérance au glucose perturbée, obésité, vieillissement, athérosclérose, syndrome X, maladies cardio-vasculaires, SIDA, cancer, cachexie, sepsie, traumatismes associés à des brûlures, malnutrition, lupus et autres maladies auto-immunes, endocrinopathies, hyperuricémie, hyperlipidémie, dyslipidémie, polykystose ovarienne ou complications liées à une activité athlétique. La méthode de traitement selon l'invention de l'insulino-résistance chez des mammifères, de préférence chez des humains, consiste a administrer au patient de l'acide succinique ou des sels dudit acide acceptables au plan pharmaceutique.
Kolesova Olga Evgenievna
Pomytkin Igor Anatolievich
Ukhanova Tatiyana Jurievna
Kolesova Olga Evgenievna
Pomytkin Igor Anatolievich
Smart & Biggar
Ukhanova Tatiyana Jurievna
Verteletsky Pavel Vasilievich
LandOfFree
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