Diazine derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) C07D 487/04 (2006.01) C07D 491/147 (2006.01)

Patent

CA 2030240

ABSTRACT PH 35517 DIAZINE DERIVATIVES The invention concerns pharmaceutically useful novel compounds of the formula I, in which ring B, R1, R2, R3, R4, R5, X and Z have the various meanings defined herein, and their non-toxic salts, and pharmaceutical compositions containing them. The novel compounds are of value in treating conditions such as hypertension and congestive heart failure. The invention further concerns processes for the manufacture of the novel compounds and the use of the compounds in medical treatment.

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