C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 271/22 (2006.01) A61K 31/325 (2006.01) A61K 31/4402 (2006.01) A61K 31/4406 (2006.01) A61P 9/06 (2006.01) C07C 235/34 (2006.01) C07D 213/79 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01)
Patent
CA 2430273
The invention relates to compounds of formula (I), wherein A1 to A8, R(1), R(2), R(3), R(4), R(30) and R(31) have the meanings as cited in the patent claims. These compounds are especially well-suited for use as novel antiarrhythmic active substances, in particular, for the treatment and prophylaxis of atrial arrhythmias, e.g. atrial fibrillations (AF) or atrial flutters.
L'invention concerne des composés de formule (I) dans laquelle A1 à A8, R(1), R(2), R(3), R(4), R(30) et R(31) ont les significations données dans les revendications. Ces composés sont particulièrement appropriés comme substances actives antiarythmiques, en particulier pour le traitement et la prophylaxie d'arythmies auriculaires, par exemple, de fibrillation auriculaire (fibrillation atriale, AF) ou de flutter auriculaire (flutter atrial).
Brendel Joachim
Hemmerle Horst
Kleemann Heinz-Werner
Peukert Stefan
Aventis Pharma Deutschland Gmbh
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis Deutschland Gmbh
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