Gene encoding candida albicans plasma membrane h+atpase

C - Chemistry – Metallurgy – 12 – N

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C12N 15/55 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 9/14 (2006.01) C12N 9/16 (2006.01)

Patent

CA 2047028

JLT8 18164 18164 TITLE OF THE INVENTION GENE ENCODING CANDIDA ALBICANS PLASMA MEMBRANE H+ATPase ABSTRACT OF THE DISCLOSURE A unique gene encoding the plasma membrane H+ATPase of the fungi Candida albicans has been isolated, purified, cloned and sequenced. The cloned gene is free of other Candida nucleic acids and is used to produce Candida albicans plasma membrane H+ATPase. The unique Candida albicans plasma membrane gene can be used to transform non-pathogenic yeast which can be used to evaluate agents capable of perturbing Candida albicans plasma membrane H+ATPase activity.

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